Sweat Test Numbers

[DietRootBeer]

Hello,



I am curious for those of you with CF that passed the sweat test what were your numbers? I think it went as follows: 0-40 normal, 40-60 grey area, 60 + CF.

I am asking this because my husband and I are both carriers. My mutation is known but they have never been able to trace my husband's mutation with all the testing that is available today.

Since my younger son cannot be confirmed with a blood test he has had 2 sweat tests: The first test he scored 9 and the second he scored 8.

He has been to the clinic before and they said they are confident he is CF free...but I always worry.

Thanks!

Mummy to 2 boys : 10 yrs old w/cf and 4 yrs old wo/cf

 

[julie]

I'm just curious here diet... I take it your older son was in the 60+ range (positive) for CF on the sweat test?

I don't have an answer to your question unfortunately but I was also curious what laboratory did your husband blood test most recently and how long ago it was? For some reason, I am fascinated with all the different mutations and testing options and such. If you don't mind sharing, I'm just curious.
I know after I had my carrier testing last year through Ambry genetics, they called about 2 months later to say they had new tests available and wanted so more blood from me.

Hope someone can share some similar experiences with you,

 

[dyza]

hi our son passed 2 tests, I think his numbers were in the mid-twentys. His pancreas works as normal, well near as damn it. We found out about his CF because of post-natal screening in Scotland.
Could you compare your youngest to your oldest's sweat test, if the oldest has an abnormal reading and has CF, then it should follow that the youngest should be the same, ( same mutations ). But everyone is diffrent, but heres hoping. Hope that helps.

 

[DietRootBeer]

Thank you for all of your quick replies...

My 10 yr old is my step-son...my husband was a single dad when I met him and when we married he was 5. He was diagnosed at birth with MI and when they did the blood test no mutations were found. I am not sure if he had a sweat test or not at birth...my husband is not sure but does not think so( 10 yrs ago!) but in his medical file there is no word of it.

Julie: He had his DNA test at the Toronto's Sick childrens Hospital. At the time ( about 3 yrs ago) they said that they would test all mutations found (like 1000) and if he had one that has never been found they could probably find it. They found nothing and said that about 15% of carriers that do not have the most common mutations cannot be found in any tests as of yet.

It is just something that is always lingering in the back of my mind. Imagine if he does have CF and we are not treating him for it. I cannot compare my CFer with my non-cfer cuz they have different mothers.

Any suggestions?

 

[Alyssa]

my kids sweat tests are 38 and 41 (read my first entry on my blog for more details) but yes, they are near the top of the normal/borderline numbers -- your child's numbers of 8 and 9 are quite low and more clearly in the normal range.

It's a good question -- I would feel the same way. I'm guessing that most people who say they have a negative or normal sweat test but genetically know they have two mutations are probably at least over 20 on the sweat test (somebody correct me if you are the exception here) But I think if a clinic has checked him out and said they really don't think he has CF, you have done all you can do for now (assuming he isn't having any symptoms) -- different story if he is presenting with some cf type issues then I would say keep pushing -- but if not, I'd say you are most likely in the clear.

 

[julie]

I see, that makes sense diet.

The only suggest I do have is to maybe redo the genetic testing. I understand that doctors concluded your older son (step son) has CF because of the MI but you aren't sure if he had a sweat test, Is that right? What I would recommend is that you do DNA testing on BOTH of them.

I know you mentioned you had done this previously, but now there are over 1,300 known mutations (I was just on the phone with somebody from Quest the other day because I want to add some of their information to my website). It might help give you peace of mind to have him/both of them tested, especially since there are at least 300 more mutations now when you had him tested a few years ago.

Other than that, best of luck and do let us know what you find out. I'm curious to know.

 

[luke]

I haven't looked at the "range" in quite sometime but do remember that a positive sweat test is >60 miliequivilants

 

[DietRootBeer]

Thanks for all the replies guys...

I spoke with my step-son's mother and she said he did have a sweat test and it was high...she does not remeber the numbers but it was used in his diagnosis of CF. So...hopefully that is a good sign.

I am going to get him tested again and I will post it.

Thanks again<img src="i/expressions/face-icon-small-smile.gif" border="0">