The Lung Ranger - detect and quantify bacteria in mucous in real-time

enniob

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Students at Dundee University are developing a device to help rapid detection and quantification (via green fluorescence) of sputum bacteria such as Pseudomonas aeruginosa or Burkholderia cenocepacia. During a competition (iGEM), they came up with the idea of the "Lung Ranger", made up of the harmless laboratory bacterium E. coli that have been engineered to glow green when other select bacteria are present.

They are building a hand-held electronic device that can be used by the patient or their GP that will rapidly detect and quantify the green fluorescence, allowing a quick and sensitive diagnosis of the presence of these pathogens.

The iGEM students have been working closely with members of the CF team at Ninewells Hospital, and have had the opportunity to meet with patients and discuss their particular issues and needs so that their project is a collaborative endeavor between researchers, healthcare practitioners and patient groups.

A great example of participatory medicine!

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- Chris Baldwin
 
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