I am on a drug study and at first couldn't take HTS. Now, I can, but my doctor would prefer I didn't since that could affect the drug study results. My PFTs have dropped slightly over the last year and I don't want to see a downward spiral begin. On the other hand, I don't want to give false results on the drug study. So, I thought I'd see what you the CF community had to say about my dilemma. HTS or not?
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To HTS or not
- Thread starter Jeana
- Start date
I am on a drug study and at first couldn't take HTS. Now, I can, but my doctor would prefer I didn't since that could affect the drug study results. My PFTs have dropped slightly over the last year and I don't want to see a downward spiral begin. On the other hand, I don't want to give false results on the drug study. So, I thought I'd see what you the CF community had to say about my dilemma. HTS or not?
I am on a drug study and at first couldn't take HTS. Now, I can, but my doctor would prefer I didn't since that could affect the drug study results. My PFTs have dropped slightly over the last year and I don't want to see a downward spiral begin. On the other hand, I don't want to give false results on the drug study. So, I thought I'd see what you the CF community had to say about my dilemma. HTS or not?
Are you on open label now and actually taking the study drug or are you, as your lung function declines (even if just a little) potentially still on the placebo?
I do think that the integrity of the trial process would be better preserved by trying not to resume a treatment you are pretty certain will change your health- since you will know any improvement won't be due to the study drug (assuming you are on the study drug and not a placebo.) However, while that is beneficial to the integrity of the trial process and overall accuracy of the results, it's not necessarily going to be good for YOU. How much longer is the trial going to last? It would be unfortunate to see you hold off on a treatment that could help you and have it turn out you've spent all this time on a placebo, but if you were on open label... I don't know. This is a hard one, weighing the individual needs of the patient against the way the whole clinical trials process works. I wish you the best in your decision.
I do think that the integrity of the trial process would be better preserved by trying not to resume a treatment you are pretty certain will change your health- since you will know any improvement won't be due to the study drug (assuming you are on the study drug and not a placebo.) However, while that is beneficial to the integrity of the trial process and overall accuracy of the results, it's not necessarily going to be good for YOU. How much longer is the trial going to last? It would be unfortunate to see you hold off on a treatment that could help you and have it turn out you've spent all this time on a placebo, but if you were on open label... I don't know. This is a hard one, weighing the individual needs of the patient against the way the whole clinical trials process works. I wish you the best in your decision.
Are you on open label now and actually taking the study drug or are you, as your lung function declines (even if just a little) potentially still on the placebo?
I do think that the integrity of the trial process would be better preserved by trying not to resume a treatment you are pretty certain will change your health- since you will know any improvement won't be due to the study drug (assuming you are on the study drug and not a placebo.) However, while that is beneficial to the integrity of the trial process and overall accuracy of the results, it's not necessarily going to be good for YOU. How much longer is the trial going to last? It would be unfortunate to see you hold off on a treatment that could help you and have it turn out you've spent all this time on a placebo, but if you were on open label... I don't know. This is a hard one, weighing the individual needs of the patient against the way the whole clinical trials process works. I wish you the best in your decision.
I do think that the integrity of the trial process would be better preserved by trying not to resume a treatment you are pretty certain will change your health- since you will know any improvement won't be due to the study drug (assuming you are on the study drug and not a placebo.) However, while that is beneficial to the integrity of the trial process and overall accuracy of the results, it's not necessarily going to be good for YOU. How much longer is the trial going to last? It would be unfortunate to see you hold off on a treatment that could help you and have it turn out you've spent all this time on a placebo, but if you were on open label... I don't know. This is a hard one, weighing the individual needs of the patient against the way the whole clinical trials process works. I wish you the best in your decision.
Are you on open label now and actually taking the study drug or are you, as your lung function declines (even if just a little) potentially still on the placebo?
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<br />I do think that the integrity of the trial process would be better preserved by trying not to resume a treatment you are pretty certain will change your health- since you will know any improvement won't be due to the study drug (assuming you are on the study drug and not a placebo.) However, while that is beneficial to the integrity of the trial process and overall accuracy of the results, it's not necessarily going to be good for YOU. How much longer is the trial going to last? It would be unfortunate to see you hold off on a treatment that could help you and have it turn out you've spent all this time on a placebo, but if you were on open label... I don't know. This is a hard one, weighing the individual needs of the patient against the way the whole clinical trials process works. I wish you the best in your decision.
<br />
<br />I do think that the integrity of the trial process would be better preserved by trying not to resume a treatment you are pretty certain will change your health- since you will know any improvement won't be due to the study drug (assuming you are on the study drug and not a placebo.) However, while that is beneficial to the integrity of the trial process and overall accuracy of the results, it's not necessarily going to be good for YOU. How much longer is the trial going to last? It would be unfortunate to see you hold off on a treatment that could help you and have it turn out you've spent all this time on a placebo, but if you were on open label... I don't know. This is a hard one, weighing the individual needs of the patient against the way the whole clinical trials process works. I wish you the best in your decision.