Two Carrier Parents

[Beccamom]

I have a diferent question. How do you know you are each carriers and that neither of you have CF. I found out I have CF because both of my children had genetic testing due to illness. They both came back with 1 genetic mutation that causes CF. However, since they each have different mutations and the same mom and the same dad. Either my husband and I were both carriers or one of us has CF. So I had the genetic testing due to my symtpoms and I have CF and gave each of my children one of my mutations.

Don't take this wrong. I am thrilled to be here and have a great life. If you had only screening for the most common genes, then it is possible one of you has CF. It is also possible one of you have a CF mutation and a 5T variant which can increase the chances of your child having CF symptoms. Maybe this is why your doctor said 50% chance. My 36 years of mis-diagnosis makes me not very trusting of doctors, so you are doing the right thing researching on your own.

Johnson:

Let me chime in here too. 2 carriers = 25% CF 50% Carrier 25% clean of mutations. Someone either mis-spoke, was misunderstood or just plain had no clue as to what they were talking about. Now if one of you have CF, what you were told would be correct.

Bill

 

[lilywing]

I often wonder about this very question. How do parents know whether they, themselves, have CF unless they are tested for ALL the mutations? I wonder too, because my dad has suffered with digestive problems his entire life, and my mother has sinus issues.