I went on tobi a little over a week ago and have been on it several times in the past during tune ups, but this time I have been having problems with it. It started out that for about 2-3 hours after my treatment my chest would feel very very tight. Within the past day or two it has felt tight ALL day. I have never needed my inhaler in the past, but in the past week I feel like I always need it. I even got up in the middle of the night to use it once.Last night I was so tight that I actually skipped a treatment and decided not to do it today either because I was afraid. I know you should never stop a drug without doctor permission, but even my inhaler wasn't soothing my tight chest and I was scared. I called my doctor, but he wasn't in and they told me he would call me later, but he hasn't called yet. I am wondering if anyone else has had this problem. And why have I used it in the past during a tune up and it didn't bother me. Is there any way to fix it or do you think I am allergic to tobi now? I am desperate for anyones input...just wish my doc would call back. Anyway let me know.Thanks