Okay so I just went looking
This article says that its not better, but not worse than CPT and can offer options in terms of getting a child to sit through it, giving the parent a break (especially with 2 CF kids, you will have one strong arm)...
<a target=_blank class=ftalternatingbarlinklarge href="http://www.ncbi.nlm.nih.gov/pubmed/17419974?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
">http://www.ncbi.nlm.nih.gov/pu...Panel.Pubmed_RVDocSum
</a>
This article discusses the increase of sputum output on patients using a vest over manual cpt.
<a target=_blank class=ftalternatingbarlinklarge href="http://www.ncbi.nlm.nih.gov/pubmed/15635998?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
">http://www.ncbi.nlm.nih.gov/pu...Panel.Pubmed_RVDocSum
</a>
My issues with any of the articles I read in this area is that their samples are very small and they have no longitudinal studies I can find. I understand why, the CF population is relatively small, so to find enough eligible participants to study this kind of thing would be tough, but statistically speaking its really hard to prove that these results are meaningful. For what its worth, I have to take all of this with a grain of salt.
Anyway, I'm revising my opinion in the post above....I think that the research mostly indicates that the real benefit of the vest lies in its ease and convenience, and that it does as well as (and possibly better by some arguments) manual CPT.