We have the In Courage and we really love it, but to my knowledge it is not machine washable. Our son used to have terrible reflux, so I know where you are coming from wanting something that can wash up. We have had no major incidents while he has been in the vest, but I have had to clean it. It washes up pretty easily with a damp towel and some mild soap. I am not sure if there are more specific instructions for cleaning it. If there are, I should find out, too! Oh, and our son was about 15 months when he started using the vest and he did not like it at all the first couple of times, but now he is used to it and will sometimes even fall asleep during the night time one. So don't get too upset if it goes badly the first couple of times, it should get better.
Angela, Mother of 7 terrific kids, including Luke, 2 years old w/CF