I was on that much vit D for a while. My levels were really low even though I was taking extra D. I tied switching the brand of vit D I was taking and that helped. I still take quite a bit 800 IU twice a day, but I was forgetting to take the 50,000 because it was only once a week. I now take the Nature Made ones. I get 400 IU with my calcium, and 400 IU by itself. At my last visit my levels were fine.