i don't have experience with asthma; only CF as my daughter has CF; though CF can display alot of symptoms similar to asthma. It's good you are having a sweat test; I hope it is negative. Unfortunately, you need no family history to have a child with CF. We has no family history of CF(that we know of); and our daughter has CF. All you need are the mother and father to be carriers of the CF mutation; then there is a 25% with each child to have CF...Hope that makes sense. Anyhow, are you seeing a pediatric pulmonologist? Has she been allergy tested? Have they done a throat culture to rule out any bacteria in her sputum...These are just a few things I would have done or ask about. If you truly want to rule out CF...You should have genetic blood work done to look for 2 CF mutations in your daughter. Hoping for a negative sweat test for your child!