Solo, your pancreas ducts get clogged with mucus, too, and when the natural digestive enzymes don't get out because of the blockages, it essentially digests itself, causing damage and scarring. So, you can have CFRD also from either the blockages or the scarring, but the enzymes pills we take don't enter the pancreas and cause damage. It's the lovely thick mucus that does it, just like it clogs up our airducts in our lungs.