Definitely! It's funny, it's pretty much considered to be one of the greatest helps to CFer's found this decade so far. And all it is, is salty water. I think the studies that came out with it, said that it helps cut hospitalizations in half.
Be prepared though- the first few times you use it will probably be uncomfortable. It made my throat raw, but it turned everything in my lungs to liquid. After using it for a month or so, it lost that affect, I'm assuming because there wasn't as much to liquify!