I have the same horrible reactions to Bactrim. I just finished a 2-week oral antibiotic course and the only thing that kept me going through it this time was the Zofran that dissolves in your mouth. Phenagren used to work, but I would throw it up as soon as I took it. This new Zofran worked amazing, but it made extremely dizzy to the point where I couldn't work. <div><br></div><div>When I have Bactrim through IV, they pre-medicate with Zofran, and then give me Phenagran.</div>