I always wondered about this myself. I had 3 kids in the house with CF. When they were in peds., I was always arguing with the head doc of our clinic because he said I should have them wear masks! Are you kidding me?! Life was tough enough on them and we felt it was important to try to have some sense of normalcy. Both my daughters grew pseudomonus, but it wasn"t until recently that my son started to grow it, (and they haven't lived together in 7 years!) So go figure. I always say that this is a crap shoot disease. They are now in their 20's. My 1 daughter passed away a few months ago, (lungs did not get to her in time) and the other two are married to non-Cf'ers. My daughter and son-in-law don't want children, not because of CF, this is just their choice, my son and daughter-in-law hope to some day. I had so many mixed feelings about the CF episode on Grey's Anatomy. I do wonder how the transplant centers feel on this subject? Would they give a transplant to a couple who both have CF? Anyway, I feel this is a personal choice. I would love to hear from any CF couples who may be out there and get their opinions.