Well I was able to handle all of it. Certainly there's gross CF stuff, but that's clinical and therefore, most people can handle it easier. Some of the sexual things are hard for some people to view. Let me see about how delicately I can put this... He nails his penis to a wooden board, then takes the nail out, and (if I remember right) it bleeds right onto the camera lens. I think that's probably the worst scene in the movie, so if you think you can handle that, you're good to go.
There's one scene that was harder for me to watch, but not because it was grotesque. It was just very graphic. He died while they were filming, right in front of the camera, so you got to see him die of the CF. He looked like a fish out of water while he was trying to breathe.
But I think it's well worthwhile to see. My mom bought it for me, and I loved it. I love any books or movies about CFers, but especially if they're true stories. <img src="i/expressions/heart.gif" border="0">