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DF508 and 3359delC Mutation
- Thread starter Dori
- Start date
My genetic counselor told me these are the specific mutations. Does this have any determination on how sick my baby is going to be?
<br />
<br />Since she is the Princess of Doom, she made sure to tell me that these are the "bad" mutations.
<br />
<br />Anyone else have these or know of anyone who does?
<br />
<br />Since she is the Princess of Doom, she made sure to tell me that these are the "bad" mutations.
<br />
<br />Anyone else have these or know of anyone who does?
H
hopesiris
Guest
Lots of us have one or two copies of DF508, it's very common. I don't know anything about the other, you may want to go to the families section and ask Ambry for more information. Genetics is only a part of the story though, so there is no way to know how the disease will present/progress.
I'm sorry that your little one has CF.
Bonnie
I'm sorry that your little one has CF.
Bonnie
H
hopesiris
Guest
Lots of us have one or two copies of DF508, it's very common. I don't know anything about the other, you may want to go to the families section and ask Ambry for more information. Genetics is only a part of the story though, so there is no way to know how the disease will present/progress.
I'm sorry that your little one has CF.
Bonnie
I'm sorry that your little one has CF.
Bonnie
H
hopesiris
Guest
Lots of us have one or two copies of DF508, it's very common. I don't know anything about the other, you may want to go to the families section and ask Ambry for more information. Genetics is only a part of the story though, so there is no way to know how the disease will present/progress.
I'm sorry that your little one has CF.
Bonnie
I'm sorry that your little one has CF.
Bonnie
H
hopesiris
Guest
Lots of us have one or two copies of DF508, it's very common. I don't know anything about the other, you may want to go to the families section and ask Ambry for more information. Genetics is only a part of the story though, so there is no way to know how the disease will present/progress.
I'm sorry that your little one has CF.
Bonnie
I'm sorry that your little one has CF.
Bonnie
H
hopesiris
Guest
Lots of us have one or two copies of DF508, it's very common. I don't know anything about the other, you may want to go to the families section and ask Ambry for more information. Genetics is only a part of the story though, so there is no way to know how the disease will present/progress.
<br />
<br />I'm sorry that your little one has CF.
<br />
<br />Bonnie
<br />
<br />I'm sorry that your little one has CF.
<br />
<br />Bonnie
K
Keepercjr
Guest
I totally agree w/ Bonnie - a person's specific mutations are only part of the story. My brother and I have/had DF508 and M1101R - my brother was sick all his life and died when he was 13 (10 years ago this month!). And yet here I am, same mutations, a fully functional adult expecting my second baby! There are modifier genes, environmental interactions, nutrition and a host of other things that will affect the severity of a persons disease. Oh and I'm pancreatic sufficient and my brother was not. I really really hate that there are genetic counselors and doctors telling people that their mutations are good or bad (or mild or severe).
I too am sorry that your baby has CF. Are you currently pregnant?
I too am sorry that your baby has CF. Are you currently pregnant?
K
Keepercjr
Guest
I totally agree w/ Bonnie - a person's specific mutations are only part of the story. My brother and I have/had DF508 and M1101R - my brother was sick all his life and died when he was 13 (10 years ago this month!). And yet here I am, same mutations, a fully functional adult expecting my second baby! There are modifier genes, environmental interactions, nutrition and a host of other things that will affect the severity of a persons disease. Oh and I'm pancreatic sufficient and my brother was not. I really really hate that there are genetic counselors and doctors telling people that their mutations are good or bad (or mild or severe).
I too am sorry that your baby has CF. Are you currently pregnant?
I too am sorry that your baby has CF. Are you currently pregnant?
K
Keepercjr
Guest
I totally agree w/ Bonnie - a person's specific mutations are only part of the story. My brother and I have/had DF508 and M1101R - my brother was sick all his life and died when he was 13 (10 years ago this month!). And yet here I am, same mutations, a fully functional adult expecting my second baby! There are modifier genes, environmental interactions, nutrition and a host of other things that will affect the severity of a persons disease. Oh and I'm pancreatic sufficient and my brother was not. I really really hate that there are genetic counselors and doctors telling people that their mutations are good or bad (or mild or severe).
I too am sorry that your baby has CF. Are you currently pregnant?
I too am sorry that your baby has CF. Are you currently pregnant?
K
Keepercjr
Guest
I totally agree w/ Bonnie - a person's specific mutations are only part of the story. My brother and I have/had DF508 and M1101R - my brother was sick all his life and died when he was 13 (10 years ago this month!). And yet here I am, same mutations, a fully functional adult expecting my second baby! There are modifier genes, environmental interactions, nutrition and a host of other things that will affect the severity of a persons disease. Oh and I'm pancreatic sufficient and my brother was not. I really really hate that there are genetic counselors and doctors telling people that their mutations are good or bad (or mild or severe).
I too am sorry that your baby has CF. Are you currently pregnant?
I too am sorry that your baby has CF. Are you currently pregnant?
K
Keepercjr
Guest
I totally agree w/ Bonnie - a person's specific mutations are only part of the story. My brother and I have/had DF508 and M1101R - my brother was sick all his life and died when he was 13 (10 years ago this month!). And yet here I am, same mutations, a fully functional adult expecting my second baby! There are modifier genes, environmental interactions, nutrition and a host of other things that will affect the severity of a persons disease. Oh and I'm pancreatic sufficient and my brother was not. I really really hate that there are genetic counselors and doctors telling people that their mutations are good or bad (or mild or severe).
<br />
<br />I too am sorry that your baby has CF. Are you currently pregnant?
<br />
<br />I too am sorry that your baby has CF. Are you currently pregnant?
I agree with the last 2 posters, I can't stand when people say they can predict what the person's life is going to be based on mutations. My dr was a bit surprised when I found out I am homozygous deltaF508. He figured I must have some weird mutation to be so healthy. But no I have "the most common and worst" and here I am 33 mother to a healthy toddler
I agree with the last 2 posters, I can't stand when people say they can predict what the person's life is going to be based on mutations. My dr was a bit surprised when I found out I am homozygous deltaF508. He figured I must have some weird mutation to be so healthy. But no I have "the most common and worst" and here I am 33 mother to a healthy toddler
I agree with the last 2 posters, I can't stand when people say they can predict what the person's life is going to be based on mutations. My dr was a bit surprised when I found out I am homozygous deltaF508. He figured I must have some weird mutation to be so healthy. But no I have "the most common and worst" and here I am 33 mother to a healthy toddler
I agree with the last 2 posters, I can't stand when people say they can predict what the person's life is going to be based on mutations. My dr was a bit surprised when I found out I am homozygous deltaF508. He figured I must have some weird mutation to be so healthy. But no I have "the most common and worst" and here I am 33 mother to a healthy toddler
I agree with the last 2 posters, I can't stand when people say they can predict what the person's life is going to be based on mutations. My dr was a bit surprised when I found out I am homozygous deltaF508. He figured I must have some weird mutation to be so healthy. But no I have "the most common and worst" and here I am 33 mother to a healthy toddler