Hi again,
Arizona State University's Biodesign program has a website that lists all of their clones.
<a target=_blank class=ftalternatingbarlinklarge href="http://dnasu.asu.edu/DNASU/GetCloneDetail.do?cloneid=287350
">http://dnasu.asu.edu/DNASU/Get...ail.do?cloneid=287350
</a>If you scroll down a bit to insert 1 and then down a bit further Coding Sequence Location, Mutations, and Discrepancies: Insert 1 you will see the Q1330E mutation listed. You will also see that the domain for this mutation,as well as the others listed,is the NBD2. I have worked with various ATP-binding cassettes,as is the region of the gene affected by your mutation, but not in the CFTR gene. From there you can do a Google scholar search for mutations in the NBD2, and you will get several articles that explain what I have previously stated above about their being two ATP binding domains, etc. These research articles can be pretty heavy, so if you come across one you need help interpreting, let me know, I will try to help as best I can...science speak can be ridiculous!
Hope this helps!