I have hyperhidrosis, I dont have CF. But the sweating never affects my arm pits, my hands and feet sweat alot, doesn't matter if i'm hot or cold, somedays its really bad, sweat will drip right off my hands, and make paper im writing on wet etc...Thebotox injections can be done for armpits, and it lasts about 6 months at a time. There also are machines you can buy, called iontophoresis machines, it uses electrical currents and water, and will help stop the sweating. You have to use it for 30 minutes at a time 2xs a day for a couple weeks to start, then a couple times a week to keep up the results. It does work, I had one, but it got to be a hassle just sitting there doing it everyday...Which would probably not be something you would want to add to your other treatment times... My bf has CF, and I don't notice that his pits sweat that much...In the summer he says when he sweats you can seee salt on his skin when it dries, and he will get salt stains on his baseball hats too...