Ok here is my experience on this. Lately, I have been wondering which way is best for me. I decided to muscle test to see if it is best to take my Enzymes before during or after a meal. I found it works for me if I take them after a few bites after a meal. Then after eating a meal, I found that I need more enzymes depending on what I eat. So I take my enzymes during and after a meal. My stomach is working much better now.
When I was in the hospital after my transplant, at first I could not eat solid foods so I put my enzymes into yogurt. The enzymes turned my yogurt into liquid. It only took a minute or two for this to work. That means that it is best to take the enzymes right after you are eating or shortly after from my experiment.
My enzymes are not the traditional enzymes so perhaps this is what works best for me.
Muscle testing is a good tool but you can test strong to something today and then after a week, you get a different answer. I retest myself when needed.