He absolutely doesn't need to miss the whole 2 weeks of school. If he's not feeling up to it, sure he can stay home. But if he's feeling better, or able to go to school, there is no problem with him taking them with him. I would notify the school nurse, and (unless he knows how to do it himself) make sure she knows how to administer the meds, and at what times. Also, I would leave the meds with her, and make sure he knows what times to go see the nurse. One thing that helps me remember when I do home IVs is SASH. Always remember SASH. Saline, Antibiotics, Saline, Heparin. It's the order in which the process goes. I might be more restrictive on recess (not only because he might be too active, but because other little kids can be unsafe with things they don't understand), but there's nothing saying he has to skip the whole 2 weeks. That's part of the reason to do home IV, so that you don't miss your normal activities. As a young adult, it gets easier, because you can do it yourself. But he still has a right to go to school while on the IV meds. I know I'm older, but I take my meds with me and administer them right in my classes. No one second questions as long as I explain to my professor what's going on. Let him do his normal stuff and go to school. It might make the 2 weeks go by faster, than if he was sitting at home doing nothing.