We also sprinkle the beads on applesauce, pears or a mixture. (Someone mentioned the Gerber plastic fruit containers- they are great and come in different fruit combinations.) When Samantha has her days that she isn't tolerating them as much, I try to get her eating and drinking first (just a little bit) AND then give her a spoonful with about half the enzyme dose. Then I let her drink a little more and then give her another spoonful.
Sometimes she just doesn't want to start with the enzymes.
Another thing we do: We purchased the little round pill containers that stack on top of one another. We store each dose of pills in the containers. We usually open them up at the beginning of the day, but some people don't feel comfortable leaving the little beads open in the containers. We have never had a problem with it. You can always leave the pills closed and just separate the amount needed per feeding in each container.
It's just a time saver, and easy to pack into your bag when you go somewhere. I also try to always have an extra bottle of enzymes in my purse. I started that after too many experiences where I didn't bring enough, thought she wouldn't be eating anything, forgot them, etc.....
Good Luck!
Maria (mother of three daughters, the youngest Samantha w/cf)