One male CF Grandchild. What's % chance of another?

C

Cheryl

New member
Our grandson was born with CF. What are the chances that if our son
has another BOY child that it will have CF?  Is there a 25%
chance, a 50% chance, or higher?  Would there  be a
decreased chance for CF if the grandchild were a girl?<br>
<br>
Does anyone know if the mutated gene will be attached to every Y
chromosome?  Or?<br>
<br>
Cheryl
 
N

NoExcuses

New member
CF is not a sex-linked disease.

Therefore, regardless of the gender, your next grandchild has a 25% chance of having CF.
 
I

IG

Guest
and a 50% chance of being a carrier of the disease (not a bad thing, but something to keep in mind), and 25% chance of not carrying the gene or having the disease.
 
J

julie

New member
Ditto what Amy and Candice have said.

Here's a link to my website <a target=_blank class=ftalternatingbarlinklarge href="http://www.cysticfibrosismaleinfertility.com/Where_to_begin_carrierTesting.html
">http://www.cysticfibrosismalei...n_carrierTesting.html
</a>This page contains a "picture" (if you will) of the probabilities of inheriting CF based on the carrier status of the parents.
 
H

harvey

New member
We had a friend who  had 6 CF kids and one non-CF. Another
friend had 4 kids, two CF and two non-CF.  It all has to do
with averages and luck but with a larger sampling the above
percentages are comforting.<br>
<br>
Harvey
 
N

NoExcuses

New member
each kid has a 1 in 4 chance. whether or not a previous birth has CF has no effect on whether or not the next kid will have CF.

For example, if you flip a coin, what you flip has nothing to do with what you flipped before.

It seems as though many people think if they have 4 kids, only one should have CF. Not the case at all. Each probability is independent for each child.
 
W

welshgirl

New member
that for me is the most upsetting thing about the randomness (not sure if that is a real word!!!!!!!!!) of cf, it seems very cruel that some families have so much worse luck than others<img src="i/expressions/face-icon-small-sad.gif" border="0">
 
D

Debra

New member
Thats why I believe that it is all in Gods hands. Deb<img src="i/expressions/heart.gif" border="0">
 
W

welshgirl

New member
do you mean god only gives cf to those who can cope? <img src="i/expressions/face-icon-small-smile.gif" border="0"> i don't really believe in it , my son does though and i am pleased about that, i feel it may help him in the times ahead.
 
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