When not in use, it is under the skin and a non-issue.
The only thing being that 1x/month you have to access long enough to flush (<20min if you know how). Otherwise, you just have a small bump under the skin where the port is located.
As for while accessed, it is cleaned & then a needle (bent 90deg) is put in the port, and secured normally with a tegraderm. You have a small tube attached that you then connect the IV's to as needed.
The nice thing, is that you can 1) access it yourself unless they put somewere odd and 2) if you want it out to shower/swim/go on a date, you just pull it out and when you are ready for your next infusion, put a new one in and you are good to go.