I have taken Megace on 2 different occasions. For me, it's not that I am close to a g-tube, it is that I have no appetite.
I have a lot of sinus issues and as a result, have no sense of taste or smell. I am obviously underweight, and we were just looking for some options for appetite stimulant. Periactin dried me up too much, Marinol made me feel funny.
Megace worked wonders, but really screwed up my montly cycle. At first, i just thought it was because I was sick, but I did some reserach and found that skipped periods can happen. Even after a month, I never "got regular." What worried my even more was that my clinic didn't seem to know about this. I stopped it on my own. I agreed to try it again a few months ago but got the same result. I will be talking to them again at my next visit. Since my husband and I are contemplating pregnancy, I need to have a regular cycle, as well as the fact that it says you are not supposed to take Megace if trying to become pregnant.
I did notice that in the shower, there was more hair in the drain than usual, but this resolved once I stopped the drug.
That being said, I would use it again later down the road if needed. It really worked well for me.
Hope this helps!