I'm talking about the plastic parts that the medicine goes in. One website says to replace them every 6 months. I got my current ones when I was in the hospital 3 years ago. I wash them in the dishwasher every couple days. Do you get new ones and if so how often? I'm fortunate to have a mild (I think) CF, but somedays I think I don't know how to do the things I'm supposed to be doing for CF care!