I have traveled in the us and outside. For drugs that need refrigeration I just put the ampules wrapped in tinfoil in a sandwich plastic baggies along with an icepack and it stays cold and easy to transport. I also carry a letter from doc about my cf and drugs I carry, yet I have NEVER had to show it. Seems the TSA has more problems with my compressor and they never question my drugs. Good luck. It is all easy to do!<br>