VX-770 Update

Mommafirst · Nov 18, 2009

I went to a talk last week where Dr. Beall (the pres. of CFF) spoke. He discussed exactly what you are saying and it is very very exciting. One pill, once a day and anyone with those mutuations could have SIGNIFICANT help with their CF. Trials thus far are showing an average of 12% PFT increases in just the first 14 days!!!!

My daughter doesn't have either of the mutations that VX-770 and VX-809 help, but I believe that this is the first step toward a more global understanding how to make a huge difference in CF care.

Atalauren (for those mutations with an X at the end) is not doing as well in clinical trials. : ( For some reason it has had great outcomes in Israel trials, but not so great in the US. I hope that this one can yield better results -- my daughter has an X mutation.

Mommafirst · Nov 18, 2009

I went to a talk last week where Dr. Beall (the pres. of CFF) spoke. He discussed exactly what you are saying and it is very very exciting. One pill, once a day and anyone with those mutuations could have SIGNIFICANT help with their CF. Trials thus far are showing an average of 12% PFT increases in just the first 14 days!!!!

My daughter doesn't have either of the mutations that VX-770 and VX-809 help, but I believe that this is the first step toward a more global understanding how to make a huge difference in CF care.

Atalauren (for those mutations with an X at the end) is not doing as well in clinical trials. : ( For some reason it has had great outcomes in Israel trials, but not so great in the US. I hope that this one can yield better results -- my daughter has an X mutation.

Mommafirst · Nov 18, 2009

I went to a talk last week where Dr. Beall (the pres. of CFF) spoke. He discussed exactly what you are saying and it is very very exciting. One pill, once a day and anyone with those mutuations could have SIGNIFICANT help with their CF. Trials thus far are showing an average of 12% PFT increases in just the first 14 days!!!!

My daughter doesn't have either of the mutations that VX-770 and VX-809 help, but I believe that this is the first step toward a more global understanding how to make a huge difference in CF care.

Atalauren (for those mutations with an X at the end) is not doing as well in clinical trials. : ( For some reason it has had great outcomes in Israel trials, but not so great in the US. I hope that this one can yield better results -- my daughter has an X mutation.

Mommafirst · Nov 18, 2009

I went to a talk last week where Dr. Beall (the pres. of CFF) spoke. He discussed exactly what you are saying and it is very very exciting. One pill, once a day and anyone with those mutuations could have SIGNIFICANT help with their CF. Trials thus far are showing an average of 12% PFT increases in just the first 14 days!!!!

My daughter doesn't have either of the mutations that VX-770 and VX-809 help, but I believe that this is the first step toward a more global understanding how to make a huge difference in CF care.

Atalauren (for those mutations with an X at the end) is not doing as well in clinical trials. : ( For some reason it has had great outcomes in Israel trials, but not so great in the US. I hope that this one can yield better results -- my daughter has an X mutation.

Mommafirst · Nov 18, 2009

I went to a talk last week where Dr. Beall (the pres. of CFF) spoke. He discussed exactly what you are saying and it is very very exciting. One pill, once a day and anyone with those mutuations could have SIGNIFICANT help with their CF. Trials thus far are showing an average of 12% PFT increases in just the first 14 days!!!!
<br />
<br />My daughter doesn't have either of the mutations that VX-770 and VX-809 help, but I believe that this is the first step toward a more global understanding how to make a huge difference in CF care.
<br />
<br />Atalauren (for those mutations with an X at the end) is not doing as well in clinical trials. : ( For some reason it has had great outcomes in Israel trials, but not so great in the US. I hope that this one can yield better results -- my daughter has an X mutation.

missT · Nov 18, 2009

Hi Mommafirst, I have read the outcome of Ataluren and maybe I am just being hopeful but it looks like its working. Ugh, I am happy for anyone who can be cured but I do not have the D508 or the other mutation with the G. I just wish this mucus would stop.

missT · Nov 18, 2009

Hi Mommafirst, I have read the outcome of Ataluren and maybe I am just being hopeful but it looks like its working. Ugh, I am happy for anyone who can be cured but I do not have the D508 or the other mutation with the G. I just wish this mucus would stop.

missT · Nov 18, 2009

Hi Mommafirst, I have read the outcome of Ataluren and maybe I am just being hopeful but it looks like its working. Ugh, I am happy for anyone who can be cured but I do not have the D508 or the other mutation with the G. I just wish this mucus would stop.

missT · Nov 18, 2009

Hi Mommafirst, I have read the outcome of Ataluren and maybe I am just being hopeful but it looks like its working. Ugh, I am happy for anyone who can be cured but I do not have the D508 or the other mutation with the G. I just wish this mucus would stop.

missT · Nov 18, 2009

Hi Mommafirst, I have read the outcome of Ataluren and maybe I am just being hopeful but it looks like its working. Ugh, I am happy for anyone who can be cured but I do not have the D508 or the other mutation with the G. I just wish this mucus would stop.

hopefulmommy · Nov 18, 2009