Dea, I have to step in and correct you here. The poster who stated type 1 diabetes is given in your genetic make up and type 2 is from damage to the pancreas is correct. Although some CFers get type 1 and some get type 2. CFRD is variably different than someone without CF who has diabetes but I checked with the University of Washington CF clinic and this is what they told me. Type 1 is more of the family history, genetics and your predisposition to diabetes-regardless of CF or not. Type 2 related to diet-for a CFer or someone without CF. Someone who eats a lot of sugars (regardless of CF status) is at a VERY high risk for damaging their pancreas because of the fluctuation of sugars through the pancreas and the body's need to recover from too much sugar or not enough sugar.
This is especially true with people who have CF because of the malabsorbtion factor-many people with CF need to eat frequently, not only because they are hungry but also because they start to feel tired, fatigued, shakey because the body did not properly digest the last meal they ate and the sugars (and calories, fat...but right now I am talking mainly sugars) they ate weren't properly absorbed by the pancreas to sustain the body for a good period of time.
Example, my husband and I both tested our sugars the other morning as soon as we got up, mine were 65 his were 62. WE ate the exact same thing (porportions and all for breakfast) 1 hour later his sugars were 224, mine were 118-a perfect example of his body immediately absorbing all the sugars in the meal and not doing as a "normal" pancreas would and sustaining them in the body so they are absorbed slowly and last longer. 2 hours after the meal we tested again and mine were 111 and his were 88, another perfect example of the fluctuation and proof that his body is not sustaining sugars in the body. Whether someone is eating a lot of sugars which is causing their Blood sugar to be very high or eating a "normal" amount of sugar and having digestive issues (like in someone with CF) there is going to be damage to the pancreas. Combine the two (which is an issue a lot of CFers are going to have-the abnormal sugar absorbtion and the wacky high sugar dites) and you have even more of a potential for diabetes-because of the damage to the pancres.
Now in Marks family they have a history of Type 1 diabetes so the doctor wants to do further testing to see if this is related to his predisposition to diabetes, his CF predisposition to diabetes or something in his diet. But a high sugar diet can cause damage to the pancreas, the pancreas then stops functioning properly and low and behold-diabetes.
Julie (wife to Mark 24 w/CF)